References - Personalising Respiratory Care in Europe

Personalised / Precision Medicine

Agusti A, Anto JM, Auffray C, Barbe F, Barreiro E, Dorca J, et al. Personalized Respiratory Medicine: Exploring the Horizon, Addressing the Issues. Am J Respir Crit Care Med 2015 Feb 15;191(4):391-401.

Agusti A. The path to personalized medicine in COPD. Thorax 2014;69(9):857-64.

Agusti A, Vestbo J. Current controversies and future perspectives in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2011 Sep 1;184(5):507-13.

Agusti A, MacNee W. The COPD control panel: towards personalised medicine in COPD. Thorax 2013;68:687-90.

Aysola RS, Hoffman EA, Gierada D et al. Airway remodeling measured by multidetector CT is increased in severe asthma and correlates with pathology. Chest. 134(6), 1183-1191 (2008).

Cholon D, Quinney N, Fulcher M, et al. Potentiator ivacaftor abrogates pharmacological correction of F508del CFTR in cystic fibrosis. Sci Trans Med. 2014;6:246ra96.

Collins FS, Green ED, Guttmacher AE, Guyer MS. A vision for the future of genomics research. Nature 2003 Apr 24;422(6934):835-47.

Collins FS, Varmus H. A New Initiative on Precision Medicine. New England Journal of Medicine 2015 Jan 30.

Elborn, J.S. Personalised medicine for cystic fibrosis: treating the basic defect. Eur Respir Rev. 2013;22:3–5

Elborn, J.S. The impact of personalised therapies on respiratory medicine. Eur Respir Rev. 2013;22:72–74

Friedman NL, Kokia E, Shemer J. Health Value Added (HVA): linking strategy, performance, and measurement in healthcare organizations. Isr Med Assoc J. 2003 Jan;5(1):3-8.

Galas DJ, Hood L. Systems biology and emerging technologies will catalyze the transition from reactive medicine to predictive, personalized, preventive and participatory (P4) medicine. IBC 2009;1(6):1-4.

Knowles MR, Drumm M. The influence of genetics on cystic fibrosis phenotypes. Cold Spring Harb Perspect Med 2012;2:a009548.

Pittman JE, Ferkol T. The evolution of cystic fibrosis care. CHEST. 2015; in press.

Schechter MS. Non-genetic influences on cystic fibrosis lung disease: the role of sociodemographic characteristics, environmental exposures, and healthcare interventions. Semin Respir Crit Care Med 2003;24:639-52.

Sethi, S. Personalised medicine in exacerbations of COPD: the beginnings. Eur Respir J 2012 40:6, 1318-1319.

Stolz DA, Meyerholz DK, Welsh M. Origins of cystic fibrosis lung disease. N Engl J Med. 2015; 372:351-62.

Stoddart A, van der Pol M, Pinnock H, Hanley J, McCloughan L, Todd A, Krishan A, McKinstry B. Telemonitoring for chronic obstructive pulmonary disease: a cost and cost-utility analysis of a randomised controlled trial. Journal of Telemedicine and Telecare 2015;21(2):108-118

Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, et al. The sequence of the human genome. Science 2001 Feb 16;291(5507):1304-51.

Woodruff PG, Agusti A, Roche N, Singh D, Martinez FJ. Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management. The Lancet 2015 May 1;385(9979):1789-98.

Telemedicine / e-Health

Cartwright M, Hirani SP, Rixon L, Beynon M, Doll H, Bower P. Whole Systems Demonstrator Evaluation Team. Effect of telehealth on quality of life and psychological outcomes over 12 months (Whole Systems Demonstrator telehealth questionnaire study): nested study of patient reported outcomes in a pragmatic, cluster randomised controlled trial, British Medical Journal 201;346:f653

Cruz J, Brooks D, Marques A. Home telemonitoring effectiveness in COPD: a systematic review. International Journal of Clinical Practice 2014;68(3):369-378

Darkins A, Ryan P, Kobb R, Foster L, Edmonson E, Wakefield B, Lancaster AE. Care Coordination/Home Telehealth: the systematic implementation of health informatics, home telehealth, and disease management to support the care of veteran patients with chronic conditions. Telemedicine Journal and e-Health 2008;14(10):1118-1126

Diez D, Agusti A, Wheelock CE. Network Analysis in the Investigation of Chronic Respiratory Diseases: from Basics to Application. Am J Respir Crit Care Med 2014 Sep 25;190(9):981-8.

Friedman, N, Raz, M Use of Computerized Medical Databases to Improve Care For Asthmatic Patients. E.R.S, Poster 2001

Goodwin N and A Alonso (2014) The Role of eHealth in Supporting Care Coordination. In Managing eHealth. From Vision to Reality,co-edited by Rosenmoller M, Whitehouse,D. and P. Wilson. Palgrave MacMillan: Basingstoke, UK, pp161-173.

Kalra D, Artmann J, Stroetmann V, and N Boye (2014) The eHealth Contribution to Person-Centred Care. In Managing eHealth. From Vision to Reality,co-edited by Rosenmoller M, Whitehouse,D. and P. Wilson. Palgrave MacMillan: Basingstoke, UK, pp174-189.

Kaye R, Kokia E, Shalev V, Idar D,. Chinitz D, Barriers and success factors in health information technology: A practitioner’s perspective. Journal of Management & Marketing in Healthcare. VOL. 3 NO. 2. PP 163–175. JUNE 2010

Kitsiou S, Pare G, Jaana M. Systematic reviews and meta-analyses of home telemonitoring interventions for patients with chronic diseases: a critical assessment of their methodological quality. Journal of Medical Internet Research 2013;15(7):e150

Kotb A, Cameron C, Hsieh S, Wells G. Comparative effectiveness of different forms of telemedicine for individuals with heart failure (HF): a systematic review and network meta-analysis. PLoS One 2015;10(2):e0118681

McDowell JE, McClean S, FitzGibbon F, Tate S. A randomised clinical trial of the effectiveness of home-based health care with telemonitoring in patients with COPD. Journal of Telemedicine and Telecare 2015;21(2):80-87

Omboni S, Gazzola T, Carabelli G, Parati G. Clinical usefulness and cost effectiveness of home blood pressure telemonitoring: meta-analysis of randomized controlled studies. Journal of Hypertension 2013;31:455-468

Palmer M, Steffen C, Iakovidis I, Giorgio F. European Commission perspective: Telemedicine for the benefit of patients, health care systems and society. Eurohealth 2009;15(1):13-15

Pinnock H, Hanley J, McCloughan L, Todd A, Krishan A, Lewis S, Stoddart A, van der Pol M, MacNee W, Sheikh A, Pagliari C, McKinstry B. Effectiveness of telemonitoring integrated into existing clinical services on hospital admission for exacerbation of chronic obstructive pulmonary disease: researcher blind, multicentre, randomised controlled trial. British Medical Journal 2013;347:f6070

Rosenbek Minet L, Hansen LW, Pedersen CD, Titlestad IL, Christensen JK, Kidholm K, Rayce K, Bowes A, Mollegard L, Early telemedicine training and counselling after hospitalization in patients with severe chronic obstructive pulmonary disease: a feasibility study. BMC Medical Informatics and Decision Making 2015;15(1):3

Wootton R, Twenty years of telemedicine in chronic disease management – an evidence synthesis. Journal Of Telemedicine And Telecare 2012;18(4):211-220


van Gaalen JL, Beerthuizen T, van der Meer V, van Reisen P, Redelijkheid GW, Snoeck-Stroband JB, Sont JK; SMASHING Study Group. Long-term outcomes of internet-based self-management support in adults with asthma: randomized controlled trial. J Med Internet Res. 2013; 12;15(9):e188.

Honkoop PJ, Taylor DR, Smith AD, Snoeck-Stroband JB, Sont JK. Early detection of asthma exacerbations by using action points in self-management Plans. Eur Respir J. 2013; 41(1):53-9.

Honkoop PJ, Loijmans RJ, Termeer EH, Snoeck-Stroband JB, Ter Riet G, Schermer TR, Sont JK; ACCURATE Study Group. Comparison between an online self-administered and an interviewer-administered version of the Asthma Control Questionnaire: a cross-sectional validation study. Prim Care Respir J. 2013; 22(3):284-9.

van der Meer V, Bakker MJ, van den Hout WB, Rabe KF, Sterk PJ, Kievit J, Assendelft WJ, Sont JK; SMASHING (Self-Management in Asthma Supported by Hospitals, ICT, Nurses and General Practitioners) Study Group. Internet-based self-management plus education compared with usual care in asthma: a randomized trial. Ann Intern Med. 2009; 151(2):110-20.

van der Meer V, van den Hout WB, Bakker MJ, Rabe KF, Sterk PJ, Assendelft WJ, Kievit J, Sont JK; SMASHING (Self-Management in Asthma Supported by Hospitals, ICT, Nurses and General Practitioners) Study Group. Cost-effectiveness of Internet-based self-management compared with usual care in asthma. PLoS One. 2011; 6(11):e27108.

van der Meer V, van Stel HF, Bakker MJ, Roldaan AC, Assendelft WJ, Sterk PJ, Rabe KF, Sont JK; SMASHING (Self-Management of Asthma Supported by Hospitals, ICT, Nurses and General practitioners) Study Group. Weekly selfmonitoring and treatment adjustment benefit patients with partly controlled and uncontrolled asthma: an analysis of the SMASHING study. Respir Res. 2010;11:74

Rikkers-Mutsaerts ER, Winters AE, Bakker MJ, van Stel HF, van der Meer V, de Jongste JC, Sont JK; SMASHING Study Group. Internet-based self-management compared with usual care in adolescents with asthma: a randomized controlled trial Pediatr Pulmonol. 2012; 47(12):1170-9.

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